Molecular Genetics Analysis of 70 Chinese Families With Muscular Dystrophy Using Multiplex Ligation-Dependent Probe Amplification and Next-Generation Sequencing

• Hauptverfasser: Dong Wang (Verfasst von), Min Gao (Verfasst von), Kaihui Zhang (Verfasst von), Ruifeng Jin (Verfasst von), Yuqiang Lv (Verfasst von), Yong Liu (Verfasst von), Jian Ma (Verfasst von), Ya Wan (Verfasst von), Zhongtao Gai (Verfasst von), Yi Liu (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background: Muscular dystrophy (MD) includes multiple types, of which dystrophinopathies caused by dystrophin (DMD) mutations are the most common types in children. An accurate identification of the causative mutation at the genomic level is critical for genetic counseling of the family, and analysi...