Molecular Genetics Analysis of 70 Chinese Families With Muscular Dystrophy Using Multiplex Ligation-Dependent Probe Amplification and Next-Generation Sequencing

• Main Authors: Dong Wang (Author), Min Gao (Author), Kaihui Zhang (Author), Ruifeng Jin (Author), Yuqiang Lv (Author), Yong Liu (Author), Jian Ma (Author), Ya Wan (Author), Zhongtao Gai (Author), Yi Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Muscular dystrophy (MD) includes multiple types, of which dystrophinopathies caused by dystrophin (DMD) mutations are the most common types in children. An accurate identification of the causative mutation at the genomic level is critical for genetic counseling of the family, and analysi...