Novel Anti-Trop2 Nanobodies Disrupt Receptor Dimerization and Inhibit Tumor Cell Growth
<b>Background:</b> Trop2 (trophoblast cell-surface antigen 2) is overexpressed in multiple malignancies and is closely associated with poor prognosis, thus positioning it as a promising target for pan-cancer therapies. Despite the approval of Trop2-targeted antibody-drug conjugates (ADCs...
Saved in:
Main Authors: | Junwen Deng (Author), Zhongmin Geng (Author), Linli Luan (Author), Dingwen Jiang (Author), Jian Lu (Author), Hanzhong Zhang (Author), Bingguan Chen (Author), Xinlin Liu (Author), Dongming Xing (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2024-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Nanobody
Published: (2021) -
Une femme trop gaie
by: Thierry Savatier
Published: (2003) -
Trop2-targeted therapy in breast cancer
by: Yixuan Hu, et al.
Published: (2024) -
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation
by: Gaetano Marverti, et al.
Published: (2024) -
Progress and Innovative Combination Therapies in Trop-2-Targeted ADCs
by: Yizhi Jiang, et al.
Published: (2024)