Generalizability of polygenic prediction models: how is the R2 defined on test data?
Abstract Background Polygenic risk scores (PRS) quantify an individual's genetic predisposition for different traits and are expected to play an increasingly important role in personalized medicine. A crucial challenge in clinical practice is the generalizability and transferability of PRS mode...
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| Main Authors: | , , , , |
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| Format: | Book |
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BMC,
2024-05-01T00:00:00Z.
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