Cover Image

Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution

Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble drug classified as BCS class IV. The present study aimed to develop novel suspended self-nanoemulsifying drug delivery system (Su-SNEDDS) to enhance the solubility and dissolution rate. The Su-SNEDDS was pre...

Full description

Saved in:

Bibliographic Details
Main Authors:	Eun Ji Park (Author), Seung Ah Choi (Author), Kyoung Ah Min (Author), Jun-Pil Jee (Author), Sung Giu Jin (Author), Kwan Hyung Cho (Author)
Format:	Book
Published:	MDPI AG, 2022-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats
by: Rae Man Kim, et al.
Published: (2018)

Preparation and Characterization of Pazopanib Hydrochloride-Loaded Four-Component Self-Nanoemulsifying Drug Delivery Systems Preconcentrate for Enhanced Solubility and Dissolution
by: Seung Ah Choi, et al.
Published: (2022)

Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability
by: Young Hoon Kim, et al.
Published: (2020)

Development and Evaluation of a Reconstitutable Dry Suspension to Improve the Dissolution and Oral Absorption of Poorly Water-Soluble Celecoxib
by: Hye-In Kim, et al.
Published: (2018)

Paliperidone-Cation Exchange Resin Complexes of Different Particle Sizes for Controlled Release
by: Jun-Pil Jee, et al.
Published: (2023)

Evaluation of Solubility, Dissolution Rate, and Oral Bioavailability of β-Cyclodextrin and Hydroxypropyl β-Cyclodextrin as Inclusion Complexes of the Tyrosine Kinase Inhibitor, Alectinib
by: Bashar J. M. Majeed, et al.
Published: (2024)

THE DISSOLUTION AND DIFFUSION OF FUROSEMIDE ON SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)
by: Iis Wahyuningsih, et al.
Published: (2017)

Solubility, pH-Solubility Profile, pH-Rate Profile, and Kinetic Stability of the Tyrosine Kinase Inhibitor, Alectinib
by: Dheyaa Tohma Madlool, et al.
Published: (2024)

A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
by: Kyeong Soo Kim, et al.
Published: (2017)

Preparation of Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS) by Co-Extrusion of Liquid SNEDDS and Polymeric Carriers-A New and Promising Formulation Approach to Improve the Solubility of Poorly Water-Soluble Drugs
by: Fabian-Pascal Schmied, et al.
Published: (2022)

SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization
by: Anne T. Larsen, et al.
Published: (2012)

Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
by: Mehran Ashfaq, et al.
Published: (2022)

Co-Amorphous Screening for the Solubility Enhancement of Poorly Water-Soluble Mirabegron and Investigation of Their Intermolecular Interactions and Dissolution Behaviors
by: Ji-Hun An, et al.
Published: (2018)

Development and Evaluation of Self-Microemulsifying Drug Delivery System for Improving Oral Absorption of Poorly Water-Soluble Olaparib
by: Yong-Han Kim, et al.
Published: (2023)

VALIDATION OF SPECTROPHOTOMETRIC METHOD TO QUANTIFY QUERCETIN IN THE IN VITRO DISSOLUTION STUDY OF SELF NANO-EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)
by: Wildan Khairi Muhtadi, et al.
Published: (2022)

Solubility and dissolution studies of tibolone polymorphs
by: Rudy Bonfilio, et al.
Published: (2018)

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment
by: Mohsin Kazi, et al.
Published: (2019)

In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility
by: Hakan Nazlı, et al.
Published: (2021)

Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
by: Alexandra Teleki, et al.
Published: (2020)

Development of black cumin seed oil (Nigella sativa L.) SNEDDS into solid-SNEDDS and its characterization
by: Rodhia Ulfa, et al.
Published: (2021)

Investigation of possible solubility and dissolution advantages of cocrystals, I: Aqueous solubility and dissolution rates of ketoconazole and its cocrystals as functions of pH
by: Jaydip M. Vasoya, et al.
Published: (2019)

Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability
by: Prakash Khadka, et al.
Published: (2014)

Multivariate Data Analysis and Central Composite Design-Oriented Optimization of Solid Carriers for Formulation of Curcumin-Loaded Solid SNEDDS: Dissolution and Bioavailability Assessment
by: Leander Corrie, et al.
Published: (2022)

Alectinib-associated drug reaction with eosinophilia and systemic symptoms syndrome
by: Sahira Farooq, BS, et al.
Published: (2020)

Application of Liquisolid Technology for Enhancing Solubility and Dissolution of Rosuvastatin
by: Pavan Ram Kamble, et al.
Published: (2014)

Engineering cocrystals of Paliperidone with enhanced solubility and dissolution characteristics
by: Radha-Rani Earle, et al.
Published: (2021)

Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam
by: Rita Ambrus, et al.
Published: (2022)

Technologies for Solubility, Dissolution and Permeation Enhancement of Natural Compounds
by: Meshal Alshamrani, et al.
Published: (2022)

Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug
by: Mayank Patel, et al.
Published: (2019)

Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers
by: Kanghee Jo, et al.
Published: (2018)

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution
by: Sooho Yeo, et al.
Published: (2020)

Symptomatic Bradycardia Due to Alectinib in a Patient with Advanced Stage of NSCLC
by: Ceva Wicaksono Pitoyo, et al.
Published: (2022)

Cilnidipine Nanocrystals, Formulation and evaluation for Optimization of solubility and Dissolution Rate
by: Suray A. Al Hazzaa, et al.
Published: (2023)

The Formulation and Characterization of Nimodipine Nanoparticles for the Enhancement of solubility and dissolution rate
by: Areej Wahhab Alhagiesa, et al.
Published: (2021)

Solubility and Dissolution Enhancement of Ebastine by Surface Solid Dispersion Technique
by: Lina S. Hussein, et al.
Published: (2021)

Improvement of the Solubility and Dissolution Characteristics of Risperidone via Nanosuspension Formulations
by: Hayder Emad, et al.
Published: (2022)

Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying
by: Mudit Dixit, et al.
Published: (2011)

Sugars and Polyols of Natural Origin as Carriers for Solubility and Dissolution Enhancement
by: Madan Sai Poka, et al.
Published: (2023)

A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies
by: Alaa Alghananim, et al.
Published: (2020)

Enhancement of solubility and dissolution rate of poorly water soluble raloxifene using microwave induced fusion method
by: Payal Hasmukhlal Patil, et al.
Published: (2013)