Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide

• Main Authors: Catherine B. Lawrence (Author), David Brough (Author), Elysse M. Knight (Author)
• Formato: Libro
• Publicado: The Company of Biologists, 2012-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

SUMMARY Obesity is associated with an increase in the prevalence and severity of infections. Genetic animal models of obesity (ob/ob and db/db mice) display altered centrally-mediated sickness behaviour in response to acute inflammatory stimuli such as lipopolysaccharide (LPS). However, the effect o...