Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide

• Principais autores: Catherine B. Lawrence (Autor), David Brough (Autor), Elysse M. Knight (Autor)
• Formato: Livro
• Publicado em: The Company of Biologists, 2012-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

SUMMARY Obesity is associated with an increase in the prevalence and severity of infections. Genetic animal models of obesity (ob/ob and db/db mice) display altered centrally-mediated sickness behaviour in response to acute inflammatory stimuli such as lipopolysaccharide (LPS). However, the effect o...