Sirtuin-6 Preserves R-spondin-1 Expression and increases Resistance of intestinal Epithelium to injury in Mice
Abstract Sirtuin-6 (Sirt6) is a critical epigenetic regulator, but its function in the gut is unknown. Here, we studied the role of intestinal epithelial Sirt6 in colitis-associated intestinal epithelial injury. We found that Sirt6, which is predominantly expressed in epithelial cells in intestinal...
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Main Authors: | Fangyi Liu (Author), Heng-Fu Bu (Author), Hua Geng (Author), Isabelle G. De Plaen (Author), Chao Gao (Author), Peng Wang (Author), Xiao Wang (Author), Jacob A. Kurowski (Author), Hong Yang (Author), Jiaming Qian (Author), Xiao-Di Tan (Author) |
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Format: | Book |
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BMC,
2017-10-01T00:00:00Z.
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