Antidepressant-like Effects of <i>Cannabis sativa</i> L. Extract in an Lipopolysaccharide Model: Modulation of Mast Cell Activation in Deep Cervical Lymph Nodes and Dura Mater

• Autors principals: Joonyoung Shin (Autor), Dong-Uk Kim (Autor), Gi-Sang Bae (Autor), Ji-Ye Han (Autor), Do-Won Lim (Autor), Young-Mi Lee (Autor), Eunjae Kim (Autor), Eunjeong Kwon (Autor), Dongwoon Han (Autor), Sungchul Kim (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2024-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Background: Lipopolysaccharide (LPS)-induced neuroinflammation is a well-established model for studying depression-like behavior, driven by pro-inflammatory cytokines such as TNF-α and IL-1β. Mast cells (MCs) contribute to neuroinflammation by releasing mediators that exacerbate depressive-like symp...