Inhibition of Peroxisome Proliferator-Activated Receptor γ Promotes Tumorigenesis Through Activation of the β-Catenin / T Cell Factor (TCF) Pathway in the Mouse Intestine

• প্রধান লেখক: Toshio Fujisawa (লেখক), Michiko Sugiyama (লেখক), Ayako Tomimoto (লেখক), Koichiro Wada (লেখক), Hiroki Endo (লেখক), Hirokazu Takahashi (লেখক), Kyoko Yoneda (লেখক), Masato Yoneda (লেখক), Masahiko Inamori (লেখক), Satoru Saito (লেখক), Yasuo Terauchi (লেখক), Takashi Kadowaki (লেখক), Naoto Tsuchiya (লেখক), Hitoshi Nakagama (লেখক), Atsushi Nakajima (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2008-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Although peroxisome proliferator-activated receptor γ (PPARγ) is strongly expressed in the intestinal epithelium, the role of PPARγ in intestinal tumorigenesis has not yet been elucidated. To address this issue, we investigated the effect of PPARγ inhibition and its mechanism on intestinal tumorigen...