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Optimizing thiopurine therapy in children with acute lymphoblastic leukemia: A promising "MINT" sequencing strategy and therapeutic "DNA-TG" monitoring

Thiopurines, including thioguanine (TG), 6-mercaptopurine (6-MP), and azathioprine (AZA), are extensively used in clinical practice in children with acute lymphoblastic leukemia (ALL) and inflammatory bowel diseases. However, the common adverse effects caused by myelosuppression and hepatotoxicity l...

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Main Authors:	Hong-Li Guo (Author), Yue-Tao Zhao (Author), Wei-Jun Wang (Author), Na Dong (Author), Ya-Hui Hu (Author), Yuan-Yuan Zhang (Author), Feng Chen (Author), Li Zhou (Author), Tao Li (Author)
Format:	Book
Published:	Frontiers Media S.A., 2022-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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