Inhibition of Phosphoinositide 3-Kinase Gamma protects endothelial cells via the Akt signaling pathway in sepsis-induced acute kidney injury

• Main Authors: Han Li (Author), Jun-Xian Xu (Author), Tiao-Chun Cheng (Author), Li-Jun Tian (Author), Jin-Feng Lin (Author), Xi Luo (Author), Zhao-Lian Bian (Author), Xu-Dong Han (Author)
• Format: Book
• Published: Karger Publishers, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Sepsis is a primary cause of death in critically ill patients and characterized by multiple organ dysfunction, including sepsis-induced acute kidney injury (AKI), which contributes to high mortality in sepsis. However, its pathophysiological mechanisms remain unclear. The kidney has on...