Inhibition of Phosphoinositide 3-Kinase Gamma protects endothelial cells via the Akt signaling pathway in sepsis-induced acute kidney injury

• Hoofdauteurs: Han Li (Auteur), Jun-Xian Xu (Auteur), Tiao-Chun Cheng (Auteur), Li-Jun Tian (Auteur), Jin-Feng Lin (Auteur), Xi Luo (Auteur), Zhao-Lian Bian (Auteur), Xu-Dong Han (Auteur)
• Formaat: Boek
• Gepubliceerd in: Karger Publishers, 2022-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: Sepsis is a primary cause of death in critically ill patients and characterized by multiple organ dysfunction, including sepsis-induced acute kidney injury (AKI), which contributes to high mortality in sepsis. However, its pathophysiological mechanisms remain unclear. The kidney has on...