mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability

• Päätekijät: Wilfrid Mazier (Tekijä), Nicolas Saucisse (Tekijä), Vincent Simon (Tekijä), Astrid Cannich (Tekijä), Giovanni Marsicano (Tekijä), Federico Massa (Tekijä), Daniela Cota (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2019-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objective: The hypothalamic paraventricular nucleus (PVN) is a key target of the melanocortin system, which orchestrates behavioral and metabolic responses depending on energy availability. The mechanistic target of rapamycin complex 1 (mTORC1) and the endocannabinoid type 1 receptor (CB1R) pathways...