mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability

• मुख्य लेखकों: Wilfrid Mazier (लेखक), Nicolas Saucisse (लेखक), Vincent Simon (लेखक), Astrid Cannich (लेखक), Giovanni Marsicano (लेखक), Federico Massa (लेखक), Daniela Cota (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2019-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: The hypothalamic paraventricular nucleus (PVN) is a key target of the melanocortin system, which orchestrates behavioral and metabolic responses depending on energy availability. The mechanistic target of rapamycin complex 1 (mTORC1) and the endocannabinoid type 1 receptor (CB1R) pathways...