LC-UV method to assay raloxifene hydrochloride in rat plasma and its application to a pharmacokinetic study

• Hauptverfasser: Márcia Camponogara Fontana (Verfasst von), João Víctor Laureano (Verfasst von), Betielli Forgearini (Verfasst von), Paula dos Santos Chaves (Verfasst von), Bibiana Verlindo de Araujo (Verfasst von), Ruy Carlos Ruver Beck (Verfasst von)
• Format: Buch
• Veröffentlicht: Universidade de São Paulo.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

A specific, precise, and accurate LC-UV method was developed and validated to assay raloxifene hydrochloride in rat plasma. Raloxifene was analyzed after liquid-liquid extraction and quantified by reversed phase liquid chromatography (C18 column) using acetonitrile and ammonium acetate buffer 0.05 M...