Anti-Inflammatory Functions of Protein C Require RAGE and ICAM-1 in a Stimulus-Dependent Manner

• Главные авторы: Natascha Braach (Автор), Kirsten Buschmann (Автор), Johanna Pflaum (Автор), Hannes Hudalla (Автор), Lutz Koch (Автор), Eduard Ryschich (Автор), Johannes Poeschl (Автор), David Frommhold (Автор)
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• Опубликовано: Hindawi Limited, 2014-01-01T00:00:00Z.
• Предметы: article
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By binding β2-integrins both ICAM-1 and the receptor for advanced glycation end products (RAGE) mediate leukocyte recruitment in a stimulus-dependent manner. Using different inflammatory mouse models we investigated how RAGE and ICAM-1 are involved in anti-inflammatory functions of protein C (PC; Ce...