Noise-Induced Cochlear Damage Involves PPAR Down-Regulation through the Interplay between Oxidative Stress and Inflammation

• Autors principals: Fabiola Paciello (Autor), Anna Pisani (Autor), Rolando Rolesi (Autor), Vincent Escarrat (Autor), Jacopo Galli (Autor), Gaetano Paludetti (Autor), Claudio Grassi (Autor), Diana Troiani (Autor), Anna Rita Fetoni (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The cross-talk between oxidative stress and inflammation seems to play a key role in noise-induced hearing loss. Several studies have addressed the role of PPAR receptors in mediating antioxidant and anti-inflammatory effects and, although its protective activity has been demonstrated in several tis...