Dapsone Azo-Linked with Two Mesalazine Moieties Is a "Me-Better" Alternative to Sulfasalazine

• Автори: Changyu Kang (Автор), Jaejeong Kim (Автор), Sanghyun Ju (Автор), Sohee Park (Автор), Jin-Wook Yoo (Автор), In-Soo Yoon (Автор), Min-Soo Kim (Автор), Yunjin Jung (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Dapsone (DpS) is an antimicrobial and antiprotozoal agent, especially used to treat leprosy. The drug shares a similar mode of action with sulfonamides. Additionally, it possesses anti-inflammatory activity, useful for treating autoimmune diseases. Here, we developed a "me-better" alternat...