Dapsone Azo-Linked with Two Mesalazine Moieties Is a "Me-Better" Alternative to Sulfasalazine

• Main Authors: Changyu Kang (Author), Jaejeong Kim (Author), Sanghyun Ju (Author), Sohee Park (Author), Jin-Wook Yoo (Author), In-Soo Yoon (Author), Min-Soo Kim (Author), Yunjin Jung (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-03-01T00:00:00Z.
• Fag: article
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Dapsone (DpS) is an antimicrobial and antiprotozoal agent, especially used to treat leprosy. The drug shares a similar mode of action with sulfonamides. Additionally, it possesses anti-inflammatory activity, useful for treating autoimmune diseases. Here, we developed a "me-better" alternat...