PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors
BCL-XL is an anti-apoptotic protein that plays an important role in tumorigenesis, metastasis, and intrinsic or therapy-induced cancer drug resistance. More recently, BCL-XL has also been identified as a key survival factor in senescent cells. Accumulation of senescent cells has been indicated as a...
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| Kopie 1 | Beschikbaar |