Anthocyanin-Rich Berry Extracts Affect SN-38-Induced Response: A Comparison of Non-Tumorigenic HCEC-1CT and HCT116 Colon Carcinoma Cells

• Egile Nagusiak: Cornelia Schmutz (Egilea), Crepelle Plaza (Egilea), Franziska Steiger (Egilea), Natascha Stoirer (Egilea), Judith Gufler (Egilea), Gudrun Pahlke (Egilea), Frank Will (Egilea), Walter Berger (Egilea), Doris Marko (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Chemotherapy with irinotecan (CPT-11), the pro-drug of the highly cytotoxic SN-38, is among the standard-of-care treatments for colorectal cancer. To counteract undesired toxic side effects on healthy tissue such as the intestinal epithelium, the use of preparations rich in polyphenols with anti-oxi...