Anthocyanin-Rich Berry Extracts Affect SN-38-Induced Response: A Comparison of Non-Tumorigenic HCEC-1CT and HCT116 Colon Carcinoma Cells

• Main Authors: Cornelia Schmutz (Author), Crepelle Plaza (Author), Franziska Steiger (Author), Natascha Stoirer (Author), Judith Gufler (Author), Gudrun Pahlke (Author), Frank Will (Author), Walter Berger (Author), Doris Marko (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy with irinotecan (CPT-11), the pro-drug of the highly cytotoxic SN-38, is among the standard-of-care treatments for colorectal cancer. To counteract undesired toxic side effects on healthy tissue such as the intestinal epithelium, the use of preparations rich in polyphenols with anti-oxi...