Preparation of Solid Dispersions of Simvastatin and Soluplus Using a Single-Step Organic Solvent-Free Supercritical Fluid Process for the Drug Solubility and Dissolution Rate Enhancement
The study was designed to investigate the feasibility of supercritical carbon dioxide (scCO<sub>2</sub>) processing for the preparation of simvastatin (SIM) solid dispersions (SDs) in Soluplus<sup>®</sup> (SOL) at temperatures below polymer's glass transition. The SIM co...
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Main Authors: | Uttom Nandi (Author), Adejumoke Lara Ajiboye (Author), Preksha Patel (Author), Dennis Douroumis (Author), Vivek Trivedi (Author) |
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Format: | Book |
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MDPI AG,
2021-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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