Targeting Premature Renal Aging: from Molecular Mechanisms of Cellular Senescence to Senolytic Trials

• मुख्य लेखकों: Rossana Franzin (लेखक), Alessandra Stasi (लेखक), Elena Ranieri (लेखक), Giuseppe Stefano Netti (लेखक), Vincenzo Cantaluppi (लेखक), Loreto Gesualdo (लेखक), Giovanni Stallone (लेखक), Giuseppe Castellano (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The biological process of renal aging is characterized by progressive structural and functional deterioration of the kidney leading to end-stage renal disease, requiring renal replacement therapy. Since the discovery of pivotal mechanisms of senescence such as cell cycle arrest, apoptosis inhibition...