Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB

• প্রধান লেখক: Kegang Linghu (লেখক), Wenqing Cui (লেখক), Taiqin Li (লেখক), Yueting Tuo (লেখক), Dasong Wang (লেখক), Huiqi Pan (লেখক), Tian Zhang (লেখক), Ligen Lin (লেখক), Hua Yu (লেখক), Xiaoxia Hu (লেখক), Haiyang Li (লেখক), Xiangchun Shen (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Rheumatoid arthritis (RA) is an inflammatory disease accompanied by abnormal synovial microenvironment (SM). Sesquiterpene lactones (SLs) are the main anti-inflammatory ingredients of many traditional herbs utilized in RA treatment. α-Methylene-γ-butyrolactone (α-M-γ-B) is a core moiety that widely...