Efficient Synthesis and Docking Analysis of Selective CDK9 Inhibitor NVP-2
Abstract Graphical Abstract NVP-2 (1), a potent and selective inhibitor of cyclin-dependent kinase 9 (CDK9), showed potent antitumor activity in preclinical studies. In this work, we designed and adopted a convergent synthetic route to efficiently synthesize NVP-2 (1). The key intermediate (7) was s...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Georg Thieme Verlag KG,
2021-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |