Exogenous 8-Hydroxydeoxyguanosine Attenuates PM<sub>2.5</sub>-Induced Inflammation in Human Bronchial Epithelial Cells by Decreasing NLRP3 Inflammasome Activation
Particulate matter 2.5 (PM<sub>2.5</sub>) induces lung injury by increasing the generation of reactive oxygen species (ROS) and inflammation. ROS aggravates NLRP3 inflammasome activation, which activates caspase-1, IL-1β, and IL-18 and induces pyroptosis; these factors propagate inflamma...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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MDPI AG,
2023-05-01T00:00:00Z.
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A1234.567 |
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