Integrin/TGF-β1 Inhibitor GLPG-0187 Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which Could Attenuate Disease Severity

• मुख्य लेखकों: Kelsey E. Huntington (लेखक), Lindsey Carlsen (लेखक), Eui-Young So (लेखक), Matthias Piesche (लेखक), Olin Liang (लेखक), Wafik S. El-Deiry (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

As COVID-19 continues to pose major risk for vulnerable populations, including the elderly, immunocompromised, patients with cancer, and those with contraindications to vaccination, novel treatment strategies are urgently needed. SARS-CoV-2 infects target cells via RGD-binding integrins, either inde...