Modulators of CFTR protein function in the treatment of cystic fibrosis - a literature review

• Egile Nagusiak: Dariusz Chojęta (Egilea), Monika Mierzwa (Egilea), Hubert Wróblewski (Egilea), Aleksandra Zimna (Egilea), Ewelina Zygmunt (Egilea), Anna Kozłowska (Egilea), Katarzyna Łysiak (Egilea)
• Formatua: Liburua
• Argitaratua: Kazimierz Wielki University, 2022-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Cystic fibrosis (CF) is a multi-system genetic disease with an autosomal recessive inheritance mechanism. The breakthroughs in the therapy of patients with CF turned out to be modulators of CFTR protein function. These small-molecule substances, influencing the basic pathogenetic defect, became a mo...