Modulators of CFTR protein function in the treatment of cystic fibrosis - a literature review

• Main Authors: Dariusz Chojęta (Author), Monika Mierzwa (Author), Hubert Wróblewski (Author), Aleksandra Zimna (Author), Ewelina Zygmunt (Author), Anna Kozłowska (Author), Katarzyna Łysiak (Author)
• Format: Book
• Published: Kazimierz Wielki University, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is a multi-system genetic disease with an autosomal recessive inheritance mechanism. The breakthroughs in the therapy of patients with CF turned out to be modulators of CFTR protein function. These small-molecule substances, influencing the basic pathogenetic defect, became a mo...