Modulators of CFTR protein function in the treatment of cystic fibrosis - a literature review

• Autors principals: Dariusz Chojęta (Autor), Monika Mierzwa (Autor), Hubert Wróblewski (Autor), Aleksandra Zimna (Autor), Ewelina Zygmunt (Autor), Anna Kozłowska (Autor), Katarzyna Łysiak (Autor)
• Format: Llibre
• Publicat: Kazimierz Wielki University, 2022-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Cystic fibrosis (CF) is a multi-system genetic disease with an autosomal recessive inheritance mechanism. The breakthroughs in the therapy of patients with CF turned out to be modulators of CFTR protein function. These small-molecule substances, influencing the basic pathogenetic defect, became a mo...