Adeno-associated virus-mediated delivery of anti-miR-199a tough decoys attenuates cardiac hypertrophy by targeting PGC-1alpha

• Asıl Yazarlar: Hualin Yan (Yazar), Hong Wang (Yazar), Xiaoxia Zhu (Yazar), Jianbo Huang (Yazar), Yifei Li (Yazar), Kaiyu Zhou (Yazar), Yimin Hua (Yazar), Feng Yan (Yazar), Da-Zhi Wang (Yazar), Yan Luo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

MicroRNAs (miRNAs) are important regulators in the process of cardiac hypertrophy and heart failure. Previous studies have shown that miR-199a is upregulated in pressure-overload cardiac hypertrophy and that inhibition of miR-199a attenuates cardiac hypertrophy in vitro. However, the therapeutic rol...