New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies
New quinoline and isatin derivatives having the main characteristics of VEGFR-2 inhibitors was synthesised. The antiproliferative effects of these compounds were estimated against A549, Caco-2, HepG2, and MDA-MB-231. Compounds 13 and 14 showed comparable activities with doxorubicin against the Caco-...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | 図書 |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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A1234.567 |
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所蔵 1 | 利用可 |