Influence of Rifampin‐Mediated Organic Anion‐Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan

Clazosentan is a selective endothelin A receptor antagonist in development for the prevention and treatment of vasospasm postsubarachnoid hemorrhage. It is a substrate of organic anion‐transporting polypeptide 1B1/1B3 based on preclinical data. This randomized, double‐blind, two‐period, cross‐over s...

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Main Authors: Pierre‐Eric Juif (Author), Christine Voors‐Pette (Author), Mike Ufer (Author), Peter Dogterom (Author), Jasper Dingemanse (Author)
Format: Book
Published: Wiley, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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