Azelnidipine Down-Regulates Renal Angiotensin-Converting Enzyme and Mineralocorticoid Receptor mRNA in Diabetic Hypertensive Rats

• Autori principali: Tetsuya Nakamura (Autore), Yuichiro Saito (Autore), Tomoko Saito (Autore), Masahiko Kurabayashi (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2006-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Effects of a new lipophilic L-type calcium channel blocker, azelnidipine, on the expression of molecular components of the renin-angiotensin-aldosterone system (RAAS) were assessed. Male Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of diabetes with hypertension, and their lean littermates...