Azelnidipine Down-Regulates Renal Angiotensin-Converting Enzyme and Mineralocorticoid Receptor mRNA in Diabetic Hypertensive Rats

Effects of a new lipophilic L-type calcium channel blocker, azelnidipine, on the expression of molecular components of the renin-angiotensin-aldosterone system (RAAS) were assessed. Male Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of diabetes with hypertension, and their lean littermates...

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Main Authors: Tetsuya Nakamura (Author), Yuichiro Saito (Author), Tomoko Saito (Author), Masahiko Kurabayashi (Author)
Formato: Livro
Publicado em: Elsevier, 2006-01-01T00:00:00Z.
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