Lipopolysaccharide Inhibits Autophagy and Promotes Inflammatory Responses via p38 MAPK-Induced Proteasomal Degradation of Atg13 in Hepatic Stellate Cells

Background. Inflammation plays a critical role in the progression of acute-on-chronic liver failure (ACLF). Atg13 is a vital regulatory component of the ULK1 complex, which plays an essential role in the initiation of autophagy. Previously, hepatic stellate cells (HSCs) were considered to be noninfl...

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Main Authors: Yuchao Wu (Author), Yajuan He (Author), Fei Wang (Author), Naijuan Yao (Author), Yingren Zhao (Author), Zhen Tian (Author)
Format: Book
Published: Hindawi Limited, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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