PS1/γ-Secretase-Mediated Cadherin Cleavage Induces β-Catenin Nuclear Translocation and Osteogenic Differentiation of Human Bone Marrow Stromal Cells

• Asıl Yazarlar: Danielle C. Bonfim (Yazar), Rhayra B. Dias (Yazar), Anneliese Fortuna-Costa (Yazar), Leonardo Chicaybam (Yazar), Daiana V. Lopes (Yazar), Hélio S. Dutra (Yazar), Radovan Borojevic (Yazar), Martin Bonamino (Yazar), Claudia Mermelstein (Yazar), Maria Isabel D. Rossi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2016-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Bone marrow stromal cells (BMSCs) are considered a promising tool for bone bioengineering. However, the mechanisms controlling osteoblastic commitment are still unclear. Osteogenic differentiation of BMSCs requires the activation of β-catenin signaling, classically known to be regulated by the canon...