Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation

• Váldodahkkit: Victor Samokhvalov (Dahkki), K. Lockhart Jamieson (Dahkki), Ahmed M. Darwesh (Dahkki), Hedieh Keshavarz-Bahaghighat (Dahkki), Tim Y. T. Lee (Dahkki), Matthew Edin (Dahkki), Fred Lih (Dahkki), Darryl C. Zeldin (Dahkki), John M. Seubert (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Linoleic acid (18:2n6, LA) is an essential n-6 PUFA which is converted to arachidonic acid (20:4n6, AA) by desaturation and elongation via...