Berberine improves central memory formation of CD8+ T cells: Implications for design of natural product-based vaccines

• Egile Nagusiak: Mingyan Li (Egilea), Yaling Wang (Egilea), Lingzhi Zhang (Egilea), Changxing Gao (Egilea), Jing J. Li (Egilea), Jiandong Jiang (Egilea), Qing Zhu (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2023-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Berberine (BBR) as one of the most effective natural products has been increasingly used to treat various chronic diseases due to its immunosuppressive/tolerogenic activities. However, it is unknown if BBR can be applied without abrogating the efforts of vaccination. Here we show that priming of CD8...