Berberine improves central memory formation of CD8+ T cells: Implications for design of natural product-based vaccines

• Main Authors: Mingyan Li (Author), Yaling Wang (Author), Lingzhi Zhang (Author), Changxing Gao (Author), Jing J. Li (Author), Jiandong Jiang (Author), Qing Zhu (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine (BBR) as one of the most effective natural products has been increasingly used to treat various chronic diseases due to its immunosuppressive/tolerogenic activities. However, it is unknown if BBR can be applied without abrogating the efforts of vaccination. Here we show that priming of CD8...