Role of EZH2-mediated epigenetic modification on vascular smooth muscle in cardiovascular diseases: A mini-review

• Main Authors: Haiyan Luo (Author), Yao Li (Author), Honghu Song (Author), Kui Zhao (Author), Wenlin Li (Author), Hailan Hong (Author), Yun-Ting Wang (Author), Luming Qi (Author), Yang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular smooth muscle cells (VSMCs) are integral to the pathophysiology of cardiovascular diseases (CVDs). Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase, plays a crucial role in epigenetic regulation of VSMCs gene expression. Emerging researches suggest that EZH2 has a dual role i...