Role of EZH2-mediated epigenetic modification on vascular smooth muscle in cardiovascular diseases: A mini-review

• Hlavní autoři: Haiyan Luo (Autor), Yao Li (Autor), Honghu Song (Autor), Kui Zhao (Autor), Wenlin Li (Autor), Hailan Hong (Autor), Yun-Ting Wang (Autor), Luming Qi (Autor), Yang Zhang (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Vascular smooth muscle cells (VSMCs) are integral to the pathophysiology of cardiovascular diseases (CVDs). Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase, plays a crucial role in epigenetic regulation of VSMCs gene expression. Emerging researches suggest that EZH2 has a dual role i...