Sodium Butyrate Alleviates Intestinal Inflammation in Mice with Necrotizing Enterocolitis

• Auteurs principaux: Qian Sun (Auteur), Yan-Chun Ji (Auteur), Zheng-Li Wang (Auteur), Xiang She (Auteur), Yu He (Auteur), Qing Ai (Auteur), Lu-Quan Li (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2021-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective. To determine the role of sodium butyrate in intestinal inflammation via regulation of high-mobility group box-1 (HMGB1), we analyzed the potential mechanism in necrotizing enterocolitis (NEC) in a neonatal mouse model. Methods. A NEC model was created with hypoxia and cold exposure and ar...