Sodium Butyrate Alleviates Intestinal Inflammation in Mice with Necrotizing Enterocolitis

• Autors principals: Qian Sun (Autor), Yan-Chun Ji (Autor), Zheng-Li Wang (Autor), Xiang She (Autor), Yu He (Autor), Qing Ai (Autor), Lu-Quan Li (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2021-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objective. To determine the role of sodium butyrate in intestinal inflammation via regulation of high-mobility group box-1 (HMGB1), we analyzed the potential mechanism in necrotizing enterocolitis (NEC) in a neonatal mouse model. Methods. A NEC model was created with hypoxia and cold exposure and ar...