Sodium Butyrate Alleviates Intestinal Inflammation in Mice with Necrotizing Enterocolitis

• Main Authors: Qian Sun (Author), Yan-Chun Ji (Author), Zheng-Li Wang (Author), Xiang She (Author), Yu He (Author), Qing Ai (Author), Lu-Quan Li (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To determine the role of sodium butyrate in intestinal inflammation via regulation of high-mobility group box-1 (HMGB1), we analyzed the potential mechanism in necrotizing enterocolitis (NEC) in a neonatal mouse model. Methods. A NEC model was created with hypoxia and cold exposure and ar...