Investigation of the profile and kinetics of degradation of rivaroxaban using HPLC, TLC-densitometry and LC/MS/MS: Application to pre-formulation studies
Rivaroxaban (RIVA), an amide group-containing oral anticoagulant was subjected to stress conditions commonly required for the registration of pharmaceuticals: base and acid-catalyzed hydrolysis (0.1 M, 60 °C, 3-6 h), oxidation (10% H2O2, 24 h), photodegradation (300-800 nm, 24 h) and thermal decompo...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Faculty of Pharmacy, Cairo University,
2015-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |