Caspase-4 Directly Activates Caspase-9 in Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells

Caspase-4 Directly Activates Caspase-9 in Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells

The present study investigated the function of caspase-4 in endoplasmic reticulum (ER) stress-induced apoptosis in human neuronal cell line SH-SY5Y. Tunicamycin, which is known to induce ER stress, activated both caspase-9 and caspase-4, and the activation of caspase-4 preceded that of caspase-9. Th...

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Bibliographic Details
Main Authors: Akiko Yamamuro (Author), Takashi Kishino (Author), Yu Ohshima (Author), Yasuhiro Yoshioka (Author), Tomoki Kimura (Author), Atsushi Kasai (Author), Sadaaki Maeda (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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