Combination Therapy of Navitoclax with Chemotherapeutic Agents in Solid Tumors and Blood Cancer: A Review of Current Evidence

• Hoofdauteurs: Nur Syahidah Nor Hisam (Auteur), Azizah Ugusman (Auteur), Nor Fadilah Rajab (Auteur), Mohd Faizal Ahmad (Auteur), Michael Fenech (Auteur), Sze Ling Liew (Auteur), Nur Najmi Mohamad Anuar (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Combination therapy emerges as a fundamental scheme in cancer. Many targeted therapeutic agents are developed to be used with chemotherapy or radiation therapy to enhance drug efficacy and reduce toxicity effects. ABT-263, known as navitoclax, mimics the BH3-only proteins of the BCL-2 family and has...