A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway

A constitutive activation of the Wnt/β-catenin pathway is an initiating event in colon carcinogenesis. We developed colon cancer cells models that highlight the non-selectivity of previously described inhibitors of the Wnt pathway and we propose our model as a suitable screening system for inhibitor...

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Bibliographic Details
Main Authors: Marina Grimaldi (Author), Abdelhay Boulahtouf (Author), Corinne Prévostel (Author), Alain Thierry (Author), Patrick Balaguer (Author), Philippe Blache (Author)
Format: Book
Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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